Terizidon

Terizidon
Nama sistematis (IUPAC)
	4,4'-{1,4-Fenilenebis[(E)metililidena; (E)azanililidena]}bis(1,2-oksazolidin-3-ona)
Data klinis
AHFS/Drugs.com	International Drug Names
Kat. kehamilan	C
Status hukum	?
Pengenal
Nomor CAS	25683-71-0
Kode ATC	J04AK03
PubChem	CID 65720
ChemSpider	59144
UNII	1199LEX5N8
KEGG	D07247
Sinonim	4-[({4-[N-(3-okso-1,2-oksazolidin-4-il)karboksimidoil]fenil}metilidena)amino]-1,2-oksazolidin-3-ona
Data kimia
Rumus	C14H14N4O4
SMILES	eMolecules & PubChem
	InChI InChI=1S/C14H14N4O4/c19-13-11(7-21-17-13)15-5-9-1-2-10(4-3-9)6-16-12-8-22-18-14(12)20/h1-6,11-12H,7-8H2,(H,17,19)(H,18,20)/b15-5+,16-6+ ; Key:ODKYYBOHSVLGNU-IAGONARPSA-N ;

Terizidon adalah obat yang digunakan dalam pengobatan tuberkulosis.^[1] Terizidon terutama digunakan dalam pengobatan tuberkulosis yang resistan terhadap banyak obat (TB-MDR) bersama dengan obat lini kedua lainnya. Obat ini merupakan turunan sikloserin dan bersifat bakteriostatik.^[2]

Referensi

^ Galietti F, Giorgis GE, Oliaro A, Boaro D, Ardizzi A, Barberis S, Massaglia GM (1991). "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Medica. 82 (7–8): 477–81. PMID 1922892.
^ Rossiter, Dawn (2012). South African Medicines Formulary. Cape Town, South Africa: Health and Medical Publishing Group of the South African Medical Association. hlm. 323–325. ISBN 978-1-875098-28-6.

Artikel bertopik antibakteri sistemik ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[1] Galietti F, Giorgis GE, Oliaro A, Boaro D, Ardizzi A, Barberis S, Massaglia GM (1991). "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Medica. 82 (7–8): 477–81. PMID 1922892.

[2] Rossiter, Dawn (2012). South African Medicines Formulary. Cape Town, South Africa: Health and Medical Publishing Group of the South African Medical Association. hlm. 323–325. ISBN 978-1-875098-28-6.

[1]

[2]


Nama sistematis (IUPAC)
4,4'-{1,4-Fenilenebis[(E)metililidena (E)azanililidena]}bis(1,2-oksazolidin-3-ona)
Data klinis
AHFS/Drugs.com	International Drug Names
Kat. kehamilan	C
Status hukum	?
Pengenal
Nomor CAS	25683-71-0^N
Kode ATC	J04AK03
PubChem	CID 65720
ChemSpider	59144^Y
UNII	1199LEX5N8^Y
KEGG	D07247^Y
Sinonim	4-[({4-[N-(3-okso-1,2-oksazolidin-4-il)karboksimidoil]fenil}metilidena)amino]-1,2-oksazolidin-3-ona
Data kimia
Rumus	C₁₄H₁₄N₄O₄
SMILES	eMolecules & PubChem
InChI InChI=1S/C14H14N4O4/c19-13-11(7-21-17-13)15-5-9-1-2-10(4-3-9)6-16-12-8-22-18-14(12)20/h1-6,11-12H,7-8H2,(H,17,19)(H,18,20)/b15-5+,16-6+^Y Key:ODKYYBOHSVLGNU-IAGONARPSA-N^Y