Infectious myonecrosis virus

Infectious myonecrosis virus ;
Penyakit	infectious myonecrosis (en)

Infectious Myonecrosis Virus adalah salah satu jenis virus RNA berutas ganda yang digolongkan dalam famili Totiviridae.^[1] Virus ini termasuk dalam famili Totiviridae yang memiliki ciri-ciri, seperti bentuk partikel ikosahedral dan memiliki diameter 40 nm. Genomnya mengkodekan protein kapsid dan RNA-dependent RNA polymerase (RdRp).^[2] Struktur IMNV tidak memiliki selubung (non-enveloped) dan panjang total genom virus ini adalah 7,560 pb yang terdiri dari dua buah Open Reading Frame (ORF), yaitu ORF 1 dan ORF 2 yang saling tumpang tindih tapi terletak pada frame yang berbeda.^[3] ORF 1 menyandikan RNA-binding protein dan protein kapsid, sedangkan ORF 2 menyandikan RNA-dependent RNA polymerase (RdRp).^[3].

Rujukan

^ Flint SJ, Enquist LW, Racaniello VR, Skalka AM. 2009. Principles of Virology. Third ed. Washington: ASM Press.
^ Senapin S, Phewsaiya K, Briggs M, Flegel TW. 2007. Outbreaks of infectious myonecrosis virus (IMNV) in Indonesia confirmed by genome sequencing and use of an alternative RT-PCR detection method. Aquaculture 266: 32 – 38.
^ ^a ^b Poulos BT, Tang KFJ, Pantoja CR, Bonami JB, Lightner DV. 2006. Purification and characterization of infectious myonecrosis virus of penaeid shrimp. J Gen Virol 87: 987 – 996.

[Flint-1] Flint SJ, Enquist LW, Racaniello VR, Skalka AM. 2009. Principles of Virology. Third ed. Washington: ASM Press.

[Senapin-2] Senapin S, Phewsaiya K, Briggs M, Flegel TW. 2007. Outbreaks of infectious myonecrosis virus (IMNV) in Indonesia confirmed by genome sequencing and use of an alternative RT-PCR detection method. Aquaculture 266: 32 – 38.

[Poulos-3] Poulos BT, Tang KFJ, Pantoja CR, Bonami JB, Lightner DV. 2006. Purification and characterization of infectious myonecrosis virus of penaeid shrimp. J Gen Virol 87: 987 – 996.

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