COG1

COG1
Pengidentifikasi
Alias	COG1, CDG2G, LDLB, component of oligomeric golgi complex 1
ID eksternal	OMIM: 606973 MGI: 1333873 HomoloGene: 8411 GeneCards: COG1
Lokasi gen (Tikus)
Kr.	Kromosom 11 (tikus)
Akhir	113,557,880 bp
Pola ekspresi RNA
	Referensi data ekspresi selengkapnya
Ontologi gen
Fungsi molekuler	• GO:0001948, GO:0016582 Ikatan protein plasma;
Komponen seluler	• Golgi membrane; • badan Golgi; • membran; • trans-Golgi network membrane; • Golgi transport complex;
Proses biologis	• protein transport; • endoplasmic reticulum to Golgi vesicle-mediated transport; • intra-Golgi vesicle-mediated transport; • Golgi organization;
	Sumber:Amigo / QuickGO
Ortolog
	9382
	16834
	ENSG00000166685
	ENSMUSG00000018661
	Q8WTW3
	Q9Z160
	NM_018714
	NM_013581
	NP_061184
	NP_038609
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Subunit oligomer golgi kompleks 1 adalah protein yang pada manusia dikodekan oleh gen COG1.^[4]^[5]

Protein yang dikodekan oleh gen ini merupakan satu dari delapan protein (Cog1-8) yang membentuk kompleks Golgi-lokal (COG) yang dibutuhkan untuk morfologi Golgi normal dan fungsinya. Diperkirakan bahwa protein ini diperlukan untuk langkah-langkah dalam pemrosesan glikokonjonjara transial dan trans Golgi yang normal dan memainkan peran dalam pengorganisasian kompleks Golgi-lokal

Interaksi

COG1 telah diketahui berinteraksi dengan COG4^[6] dan COG3.^[7]

Referensi

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018661 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M (Mar 1999). "Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex". Proc Natl Acad Sci U S A. 96 (3): 915–20. doi:10.1073/pnas.96.3.915. PMC 15325  . PMID 9927668.
^ "Entrez Gene: COG1 component of oligomeric golgi complex 1".
^ Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. United States. 279 (23): 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703.
^ Loh, Eva; Hong Wanjin (Jun 2002). "Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp". J. Biol. Chem. United States. 277 (24): 21955–61. doi:10.1074/jbc.M202326200. ISSN 0021-9258. PMID 11929878.

Pranala luar

GeneReviews/NCBI/NIH/UW masuk pada Gangguan Bawaan dari Glikosilasi Gambaran
Manusia Lokasi genom COG1 manusia dan halaman rincian gen COG1 dalam UCSC Genome Browser.UCSC Genome BrowserLokasi genom COG1 manusia dan halaman rincian gen COG1 dalam UCSC Genome Browser.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000018661 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9927668-4] Chatterton JE, Hirsch D, Schwartz JJ, Bickel PE, Rosenberg RD, Lodish HF, Krieger M (Mar 1999). "Expression cloning of LDLB, a gene essential for normal Golgi function and assembly of the ldlCp complex". Proc Natl Acad Sci U S A. 96 (3): 915–20. doi:10.1073/pnas.96.3.915. PMC 15325  . PMID 9927668.

[entrez-5] "Entrez Gene: COG1 component of oligomeric golgi complex 1".

[pmid15047703-6] Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. United States. 279 (23): 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703.

[pmid11929878-7] Loh, Eva; Hong Wanjin (Jun 2002). "Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp". J. Biol. Chem. United States. 277 (24): 21955–61. doi:10.1074/jbc.M202326200. ISSN 0021-9258. PMID 11929878.

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